Name: B-hEPO mice
Brand: Biocytogen
SKU: 112458

B-hEPO mice

Catalog Number: 112458

Strain Name: C57BL/6N-Epo^{tm1(EPO)Bcgen}/Bcgen

Strain Background: C57BL/6N

NCBI gene ID: 2056 (Human)

Aliases: EP; DBAL; ECYT5; MVCD2

---

可提供授权方案

获取报价

Targeting strategy

Gene targeting strategy for B-hEPO mice. The exons 1-5 of mouse Epo gene that encodes the full-length protein were replaced by human EPO exons 1-5 in B-hEPO mice.

Protein expression analysis

Strain specific EPO expression analysis in homozygous B-hEPO mice by ELISA. Serum were isolated from wild-type C57BL/6 mice (+/+) and homozygous B-hEPO mice (H/H) and analyzed by ELISA with species-specific EPO ELISA kit. Mouse EPO was detectable in wild-type mice (A). Human EPO was exclusively detectable in homozygous B-hEPO mice but not in wild-type mice (B).* 1 ng/mL=21.2 miu/L

* When publishing results obtained using this animal model, please acknowledge the source as follows: The animal model [B-hEPO mice] (Cat# 112458) was purchased from Biocytogen.

B-hEPO mice

B-hEPO mice

海报

发表文章

相关产品

Targeting strategy

Protein expression analysis